Harvard Study: Coffee Consumption Reduces Dementia Risk by 18% Over 43-Year Research Period

10.02.2026
Harvard Study: Coffee Consumption Reduces Dementia Risk by 18% Over 43-Year Research Period

A comprehensive longitudinal study conducted by Harvard researchers has revealed significant neuroprotective benefits of regular coffee consumption against dementia. The research, spanning 43 years and involving 130,000 participants, demonstrates compelling evidence for coffee's cognitive health benefits.

The study findings indicate that individuals who consume coffee regularly exhibited an 18% lower risk of developing dementia compared to non-consumers. The research team identified specific mechanisms through which caffeine provides neuroprotection:

• Prevention of neuronal activity deceleration in brain cells
• Reduction in beta-amyloid accumulation, a key biomarker associated with Alzheimer's disease

Regarding optimal consumption levels, the research established that 2-3 cups of coffee or 1-2 cups of tea daily provided the most effective protective effects. The study notes that exceeding these recommended amounts does not yield proportionally greater benefits and may potentially introduce cardiovascular complications.

Source: JAMA Network

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